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Ticker
UPB

Price
29.86
Stock movement up
+1.53 (5.40%)
Company name
Upstream Bio, Inc.
Exchange
(NASDAQ
,
Currency
USD
)
Sector
Healthcare >
Biotechnology
Market cap
1.61B
Ent value
1.55B
Price/Sales
576.49
Price/Book
4.26
Div yield
-
Div growth
-
Growth years
-
FCF payout
-
Trailing P/E
-
Forward P/E
-
PEG
-
EPS growth
-
1 year return
57.08%
3 year return
-
5 year return
-
10 year return
-
Last updated: 2025-12-18

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DIVIDENDS

UPB does not pay dividends or no data was received

iO Charts is a Seeking Alpha partner

VALUATION

Valuation Ratios

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Valuation Ratios data
Trailing P/E-
Price to OCF-
Price to FCF-
Price to EBITDA-
EV to EBITDA-

Valuation (Sales/Book Value)

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Valuation (Sales/Book Value) data
Price to Sales576.49
Price to Book4.26
EV to Sales555.21

iO Charts is a Seeking Alpha partner

iO Charts is a Seeking Alpha partner

FINANCIALS

Per share

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Per share data
Current share count54.04M
EPS (TTM)-
FCF per share (TTM)-

Income statement

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Income statement data
Revenue (TTM)-
Gross profit (TTM)-
Operating income (TTM)-
Net income (TTM)-
EPS (TTM)-
EPS (1y forward)-3.21

Margins

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Margins data
Gross margin (TTM)-
Operating margin (TTM)-
Profit margin (TTM)-

Balance Sheet

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Balance Sheet data
Cash72.16M
Net receivables683.00K
Total current assets389.02M
Goodwill0.00
Intangible assets0.00
Property, plant and equipment2.27M
Total assets391.19M
Accounts payable3.95M
Short/Current long term debt1.42M
Total current liabilities11.91M
Total liabilities12.61M
Shareholder's equity378.58M
Net tangible assets0.00

Cash flow

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Cash flow data
Operating cash flow (TTM)-
Capital expenditures (TTM)-
Free cash flow (TTM)-
Dividends paid (TTM)-

Financial returns

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Financial returns data
Return on Equity-
Return on Assets-
Return on Invested Capital-
Cash Return on Invested Capital-

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STOCK INFORMATION

Stock chart

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Stock price data
Open29.09
Daily high30.27
Daily low28.36
Daily Volume790K
All-time high29.86
1y analyst estimate49.75
Beta-
EPS (TTM)-
Dividend per share0.00
Ex-div date-
Next earnings date11 Mar 2026

Downside potential

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Downside potential data
UPBS&P500
Current price drop from All-time high-3.38%-2.58%
Highest price drop-77.84%-19.00%
Date of highest drop8 Apr 20258 Apr 2025
Avg drop from high-41.51%-2.63%
Avg time to new high27 days6 days
Max time to new high264 days89 days

iO Charts is a Seeking Alpha partner

iO Charts is a Seeking Alpha partner

COMPANY DETAILS
UPB (Upstream Bio, Inc.) company logo
Marketcap
1.61B
Marketcap category
Small-cap
Description
Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. Its product candidate includes verekitug, which is in Phase 2 clinical development for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps, as well as in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.
Employees
52
Investor relations
-
SEC filings
CEO
Country
USA
City
Stock type
-
CCC status
-
Dividend Frequency
-
EVENTS AND PRESENTATIONS
EventsPresentations
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iO Charts is a Seeking Alpha partner

iO Charts is a Seeking Alpha partner

UNDERSTAND THE BUSINESS
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COMPANY NEWS