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- Ticker
- UPB
- Price
- 31.79
- Stock movement up
- +0.20 (0.63%)
- Company name
- Upstream Bio, Inc.
- Exchange
- (NASDAQ ,
- Currency
- USD )
- Sector
- Healthcare >Biotechnology
- Market cap
- 1.72B
- Ent value
- 1.66B
- Price/Sales
- 613.75
- Price/Book
- 4.54
- Div yield
- -
- Div growth
- -
- Growth years
- -
- FCF payout
- -
- Trailing P/E
- -
- Forward P/E
- -
- PEG
- -
- EPS growth
- -
- 1 year return (CAGR)
- 194.08%
- 3 year return (CAGR)
- -
- 5 year return (CAGR)
- -
- 10 year return (CAGR)
- -
Last updated: 2026-01-22
iO Charts is a Seeking Alpha partner
iO Charts is a Seeking Alpha partner
DIVIDENDS
UPB does not pay dividends or no data was received
iO Charts is a Seeking Alpha partner
iO Charts is a Seeking Alpha partner
VALUATION
Valuation Ratios
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Valuation Ratios data
| Trailing P/E | - |
| Price to OCF | - |
| Price to FCF | - |
| Price to EBITDA | - |
| EV to EBITDA | - |
Valuation (Sales/Book Value)
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Valuation (Sales/Book Value) data
| Price to Sales | 613.75 |
| Price to Book | 4.54 |
| EV to Sales | 592.47 |
iO Charts is a Seeking Alpha partner
iO Charts is a Seeking Alpha partner
FINANCIALS
Per share
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Per share data
| Current share count | 54.04M |
| EPS (TTM) | -2.27 |
| FCF per share (TTM) | -2.27 |
Income statement
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Income statement data
| Revenue (TTM) | 2.80M |
| Gross profit (TTM) | 2.77M |
| Operating income (TTM) | -140.51M |
| Net income (TTM) | -122.23M |
| EPS (TTM) | -2.27 |
| EPS (1y forward) | -3.21 |
Margins
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Margins data
| Gross margin (TTM) | 98.89% |
| Operating margin (TTM) | -5020.08% |
| Profit margin (TTM) | -4366.77% |
Balance Sheet
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Balance Sheet data
| Cash | 72.16M |
| Net receivables | 683.00K |
| Total current assets | 389.02M |
| Goodwill | 0.00 |
| Intangible assets | 0.00 |
| Property, plant and equipment | 2.27M |
| Total assets | 391.19M |
| Accounts payable | 3.95M |
| Short/Current long term debt | 1.42M |
| Total current liabilities | 11.91M |
| Total liabilities | 12.61M |
| Shareholder's equity | 378.58M |
| Net tangible assets | 0.00 |
Cash flow
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Cash flow data
| Operating cash flow (TTM) | -122.26M |
| Capital expenditures (TTM) | 279.00K |
| Free cash flow (TTM) | -122.53M |
| Dividends paid (TTM) | 0.00 |
Financial returns
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Financial returns data
| Return on Equity | -32.28% |
| Return on Assets | -31.24% |
| Return on Invested Capital | -32.22% |
| Cash Return on Invested Capital | -32.31% |
iO Charts is a Seeking Alpha partner
iO Charts is a Seeking Alpha partner
STOCK INFORMATION
Stock chart
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Stock price data
| Open | 31.74 |
| Daily high | 32.52 |
| Daily low | 31.70 |
| Daily Volume | 397K |
| All-time high | 32.60 |
| 1y analyst estimate | 49.75 |
| Beta | - |
| EPS (TTM) | -2.27 |
| Dividend per share | 0.00 |
| Ex-div date | - |
| Next earnings date | 11 Mar 2026 |
Downside potential
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Downside potential data
| UPB | S&P500 | |
| Current price drop from All-time high | -2.48% | -0.89% |
| Highest price drop | -77.84% | -19.00% |
| Date of highest drop | 8 Apr 2025 | 8 Apr 2025 |
| Avg drop from high | -39.03% | -2.49% |
| Avg time to new high | 23 days | 6 days |
| Max time to new high | 264 days | 89 days |
iO Charts is a Seeking Alpha partner
iO Charts is a Seeking Alpha partner
COMPANY DETAILS
Marketcap
1.72B
Marketcap category
Small-cap
Description
Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases focusing on severe respiratory disorders. It offers verekitug, which is in Phase 2 clinical development for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps, and in Phase I clinical trial for treating chronic obstructive pulmonary disease. The company was incorporated in 2021 and is headquartered in Waltham, Massachusetts.
Employees
52
Website
Investor relations
-
SEC filings
CEO
Country
USA
City
Stock type
-
CCC status
-
Dividend Frequency
-
EVENTS AND PRESENTATIONS
EventsPresentations
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iO Charts is a Seeking Alpha partner
iO Charts is a Seeking Alpha partner
UNDERSTAND THE BUSINESS
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COMPANY NEWS
Seeking AlphaPress releases
iO Charts is a Seeking Alpha partner